BDBM50420427 CHEMBL2089346

SMILES O[C@@H]1[C@@H]2C[C@@H]2[C@H]([C@@H]1O)n1cnc2c(NCCc3ccccc3)nc(nc12)C#Cc1ccccc1

InChI Key InChIKey=FYDDTVMINURRAI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420427   

TargetAdenosine receptor A3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420427(CHEMBL2089346)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420427(CHEMBL2089346)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]I-AB-MECA from recombinant human A3AR expressed in HEK293 cell membranes measured after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420427(CHEMBL2089346)
Affinity DataKi:  20nMAssay Description:Antagonist activity at A3 adenosine receptor (unknown origin) assessed as inhibition of adenylate cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50420427(CHEMBL2089346)
Affinity DataKi:  480nMAssay Description:Displacement of [125I]I-AB-MECA from recombinant mouse A3AR expressed in HEK293 cell membranes measured after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Mouse)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50420427(CHEMBL2089346)
Affinity DataKi:  480nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse adenosine A3 receptor expressed in HEK293 cell membranes aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed