BDBM50420732 CHEMBL2087495

SMILES CNc1ncc(cn1)-c1nc(N2CCOCC2)c2nc(CN3CCN(CC3)S(C)(=O)=O)cn2c1Cl

InChI Key InChIKey=IISVATQKJZBIJX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420732   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL

LigandBDBM50420732(CHEMBL2087495)Copy SMILESCopy InChI

Affinity DataIC50: 11.4nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/22/2013
Entry Details Article
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