BDBM50420800 CHEMBL2088036

SMILES COC(=O)CN1CN(c2ccccc2)C2(CCN(Cc3cccc4ccccc34)CC2)C1=O

InChI Key InChIKey=AQMPIDSGLFVVPL-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50420800   

TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human NOPR expressed in human BHK cells assessed as inhibition of forskolin-mediated cAMP accumulation after 10 mins by radioimmu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataEC50:  121nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420800(CHEMBL2088036)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed