BDBM50420802 CHEMBL2088034

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)[C@H]1CC[C@@H]2CCCc3cccc1c23

InChI Key InChIKey=JLFMYEAXZNPWBK-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420802   

TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420802(CHEMBL2088034)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420802(CHEMBL2088034)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420802(CHEMBL2088034)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420802(CHEMBL2088034)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420802(CHEMBL2088034)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed