BDBM50420809 CHEMBL2088038::CHEMBL2088039

SMILES CN(C)C(=O)C(CN1CCC2(CC1)OCCc1ccsc21)Cn1cccn1

InChI Key InChIKey=JEMCPFWOAWEARU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420809   

TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420809(CHEMBL2088038 | CHEMBL2088039)
Affinity DataKi:  2.05nMAssay Description:Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420809(CHEMBL2088038 | CHEMBL2088039)
Affinity DataKi:  7.40nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420809(CHEMBL2088038 | CHEMBL2088039)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420809(CHEMBL2088038 | CHEMBL2088039)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420809(CHEMBL2088038 | CHEMBL2088039)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed