BDBM50420930 CHEMBL2087795

SMILES COc1nn2c(cccc2c1N(CC1CC1)CC1CCOCC1)-c1c(OC)cc(C)cc1OC

InChI Key InChIKey=HVIGQBJIPSWMAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420930   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420930(CHEMBL2087795)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50420930(CHEMBL2087795)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed