BDBM50420954 CHEMBL2088089
SMILES Cc1cc(Nc2nc(NCCc3cccnc3)ncc2Br)[nH]n1
InChI Key InChIKey=UOHJGIQDKUHCQV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50420954
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human FGFR1 phosphorylation expressed in COS1 cells after 1 hr by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human KDR phosphorylation expressed in VEGF-stimulated HUVEC treated 90 mins before VEGF stimulation measured after 5 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human INSR phosphorylation over expressed in CHOT cells after 60 mins by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human IGF1R phosphorylation expressed in IGF-1-stimulated knockout mouse R+ cells treated 30 mins before IGF-1 stimulation measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of recombinant N terminal GST-tagged human FGFR1 (456 to 765) expressed in baculovirus infected Sf21 cells after 40 mins by caliper mobili...More data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Inhibition of recombinant N terminal GST-tagged human KDR (805 to 1356) expressed in baculovirus infected Sf9 cells after 90 mins by caliper mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant N terminal His6-tagged human IGF1R (959 to end) expressed in baculovirus infected Sf21 cells after 80 mins by caliper mobil...More data for this Ligand-Target Pair