BDBM50421293 CHEMBL2087881

SMILES CO[C@@H]1CC[C@H]1CNc1ncnc2[nH]c(c(-c3ccccc3)c12)-c1ccc(OCCN(C)C)cc1

InChI Key InChIKey=IZQHOXWWRDCUSH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50421293   

TargetActivated CDC42 kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50421293(CHEMBL2087881)
Affinity DataKi:  20nMAssay Description:Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells assessed as inhibition of autophosphorylation after 2 hrs by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50421293(CHEMBL2087881)
Affinity DataIC50: 420nMAssay Description:Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed