BDBM50421536 CHEMBL89245

SMILES Fc1ccc(cc1)N(C1CCNCC1)C(=O)CCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DORXFPYAVMERKG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421536   

TargetSubstance-P receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50421536(CHEMBL89245)
Affinity DataKi:  200nMAssay Description:Negative logarithm causing 50% receptor occupancy against tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50421536(CHEMBL89245)
Affinity DataIC50: 200nMAssay Description:Binding affinity at human Tachykinin receptor 1 expressed in CHO cells by [3H]-substance P displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50421536(CHEMBL89245)
Affinity DataKi:  251nMAssay Description:Negative logarithm causing 50% receptor occupancy against serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421536(CHEMBL89245)
Affinity DataIC50: 251nMAssay Description:Binding affinity at serotonin transporter from rat cerebral cortex by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed