BDBM50421556 CHEMBL109183

SMILES FC(F)(F)c1cc(COCC(N2CCNCC2)c2ccc(Cl)c(Cl)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=WBWPKPCFEIYLFZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421556   

TargetSubstance-P receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421556(CHEMBL109183)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421556(CHEMBL109183)
Affinity DataIC50:  5nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in CHO cells using [3H]-substance P as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rat)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50421556(CHEMBL109183)
Affinity DataIC50:  200nMAssay Description:Binding affinity against Serotonin transporter in rat cerebral cortex using [3H]paroxetine binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed