BDBM50421951 CHEMBL1744002
SMILES COc1ccc(CN2CCC3(CCCc4ccccc34)CC2)cc1
InChI Key InChIKey=PUCIJQFBXXTCMC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50421951
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataKi: 206nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:In vitro for the binding affinity against dopamine receptor D2 by using [3H](-)-sulpiride as radioligand in rat striatum.More data for this Ligand-Target Pair