BDBM50422691 CHEMBL189843

SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCCc4ccccc34)C(F)(F)F)cc12

InChI Key InChIKey=SEXWDRQEUDFISX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422691   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422691(CHEMBL189843)
Affinity DataIC50: 145nMAssay Description:Glucocorticoid receptor mediated transrepression of NFkB reporter gene in human A549 lung epithelial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422691(CHEMBL189843)
Affinity DataIC50: 708nMAssay Description:Antagonist activity for Glucocorticoid receptor in MMTV transactivation assay in human A549 lung epithelial cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422691(CHEMBL189843)
Affinity DataIC50: 708nMAssay Description:Antagonist activity for Glucocorticoid receptor in MMTV transactivation assay in human A549 lung epithelial cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed