BDBM50422752 CHEMBL5284731

SMILES CN1CCN(Cc2ccc(NC(=O)c3cnc(C)c(c3)C#Cc3c(N)ncc4ccc(F)cc34)cc2C(F)(F)F)CC1

InChI Key InChIKey=NLTPJGABPAYONH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50422752   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50422752(CHEMBL5284731)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLT3-ITD mutant phosphorylation in human MOLM-14 cell incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50422752(CHEMBL5284731)
Affinity DataIC50: 17nMAssay Description:Inhibition of FLT3-D835Y mutant phosphorylation in human MOLM-14 cell incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed