BDBM50423653 CHEMBL2087786

SMILES O[C@@H](COc1cccc2ncccc12)CN1CCN(CC1)[C@@H]1c2ccccc2[C@@H]2[C@H](c3ccccc13)C2(Cl)Cl

InChI Key InChIKey=ISHQZWGKIWGKBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50423653   

TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50423653(CHEMBL2087786)
Affinity DataIC50: 400nMAssay Description:Inhibition of P-gp (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50423653(CHEMBL2087786)
Affinity DataIC50: 930nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed