BDBM50424406 CHEMBL2315070

SMILES Nc1ncc(-c2cccnc2)c2scc(-c3cccc(NC(=O)Cc4ccccc4)c3)c12

InChI Key InChIKey=GUGOWVXOJCARSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424406   

TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50424406(CHEMBL2315070)
Affinity DataIC50: 19nMAssay Description:Inhibition of B-Raf (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50424406(CHEMBL2315070)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of B-Raf (unknown origin) expressed in mouse 3T3 cells co-expressing FLAG-tagged MEK1 assessed as inhibition of MEK1 phosphorylation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed