BDBM50424472 CHEMBL2316386

SMILES CS(=O)Cc1ccc(C(=O)Nc2ccc(OCCOCCO)nc2C(=O)NCC2CCC2)c2ccccc12

InChI Key InChIKey=UBFBCNIBTXDRJO-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50424472   

TargetCannabinoid receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424472(CHEMBL2316386)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424472(CHEMBL2316386)
Affinity DataIC50:  7.20nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424472(CHEMBL2316386)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424472(CHEMBL2316386)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424472(CHEMBL2316386)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed