BDBM50424477 CHEMBL2316379

SMILES O=C(NCC1CCOCC1)c1ncccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12

InChI Key InChIKey=SBMZVMAQHHRTLR-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50424477   

TargetCannabinoid receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424477(CHEMBL2316379)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424477(CHEMBL2316379)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424477(CHEMBL2316379)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424477(CHEMBL2316379)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424477(CHEMBL2316379)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed