BDBM50424537 CHEMBL2312142

SMILES COc1cc(Nc2cc(ccn2)-c2cccc(c2)C#N)ccc1N1CCN(C)CC1

InChI Key InChIKey=YTRKGSFSZXFLJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424537   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424537(CHEMBL2312142)
Affinity DataIC50: 6nMAssay Description:Inhibition of TNIK (unknown origin) by ADP glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424537(CHEMBL2312142)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424537(CHEMBL2312142)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of TNIK-mediated TCF4/beta-casein transcription in human HCT116 cells by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed