BDBM504247 (R)-N-(6-(4-(2,2- Difluoroethyl)piperidin-1-yl)-2- (2-fluoro-3-hydroxy-3- methylbutyl)-1-oxoisoindolin-5- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 96
SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCC(CC(F)F)CC1
InChI Key InChIKey=RXUWXMWVIFQHIE-JOCHJYFZSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 504247
Affinity DataKi: 1.5nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair