BDBM50425133 CHEMBL2313257

SMILES CCNC(=O)c1ccc2nc(C)c3nnc(-c4cncc(OC)c4)n3c2c1

InChI Key InChIKey=UMJOYABDDYRKPH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425133   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425133(CHEMBL2313257)Copy SMILESCopy InChI

Affinity DataIC50: 8.90nMAssay Description:Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425133(CHEMBL2313257)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL