BDBM50425377 CHEMBL2316493

SMILES OC[C@@H](O)COc1ccc2CCc3cc(Nc4ccc(F)c(NC(=O)c5cccs5)c4)ccc3C(=O)c2c1

InChI Key InChIKey=AOJWJIKBZQTQGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425377   

TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50425377(CHEMBL2316493)
Affinity DataIC50: 7nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50425377(CHEMBL2316493)
Affinity DataIC50: 42nMAssay Description:Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed