BDBM50425817 CHEMBL2316909

SMILES COc1cccc(c1)C#Cc1c(oc2cc(O)c(cc12)C(O)=O)-c1ccccc1

InChI Key InChIKey=LMUDZCADMSVBHA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50425817   

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of LYP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TCPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425817BDBM50425817(CHEMBL2316909)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CD45 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed