BDBM50425891 CHEMBL2312666

SMILES NC(=O)C(=O)N1CCc2c(C1)c(nn2CCCN1CCSCC1)-c1ccc(Cl)c(c1)C#Cc1ccc(CNCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=TZUDZPIBLDXFKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425891   

TargetCathepsin S(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425891(CHEMBL2312666)
Affinity DataIC50: 30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425891(CHEMBL2312666)
Affinity DataIC50: 270nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as invariant chain-li degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed