BDBM50426316 CHEMBL2321963

SMILES O=Nc1c(C2C(=O)Nc3c2cccc3C(F)(F)F)[nH]c2cc(C(=O)O)ccc12

InChI Key InChIKey=GDXXWQNHNKGHNI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50426316   

TargetCyclin-dependent kinase 5(Human)
University of Athens

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426316BDBM50426316(CHEMBL2321963)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50426316BDBM50426316(CHEMBL2321963)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Athens

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426316BDBM50426316(CHEMBL2321963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Pig)
University of Athens

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426316BDBM50426316(CHEMBL2321963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Athens

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426316BDBM50426316(CHEMBL2321963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed