BDBM50426619 CHEMBL2326175

SMILES CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1ncn(C)n1

InChI Key InChIKey=QHNXJRSEHMJHRM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50426619   

TargetAlpha-1A adrenergic receptor(Bovine)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50426619(CHEMBL2326175)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]prazosine from bovine alpha1A adrenoceptor expressed in BHK cells after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50426619(CHEMBL2326175)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]prazosine from hamster alpha1B adrenoceptor expressed in Rat1 cells after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50426619(CHEMBL2326175)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]prazosine from rat alpha1D adrenoceptor expressed in CHO cells after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50426619(CHEMBL2326175)
Affinity DataKi:  89nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50426619(CHEMBL2326175)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed