BDBM50426665 CHEMBL2326476

SMILES Nc1nc2cc3CCN(Cc4ccccc4)CCc3cc2s1

InChI Key InChIKey=RRGCMCQNBGLNIY-UHFFFAOYSA-N

Data  1 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426665   

TargetD(2) dopamine receptor(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50426665(CHEMBL2326476)Copy SMILESCopy InChI

Affinity DataKi:  80nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetD(2) dopamine receptor(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50426665(CHEMBL2326476)Copy SMILESCopy InChI

Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at human D2 dopamine receptor expressed in CHO cell membrane by GTPgammaS-binding assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50426665(CHEMBL2326476)Copy SMILESCopy InChI

Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL