BDBM50427008 CHEMBL2326864

SMILES CC(=O)Nc1nc(CCc2ccc(N=C(N)N)cc2)cs1

InChI Key InChIKey=HKWOSPCVGDKYBR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50427008   

TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat VAP1 expressed in CHO cells using [14C]-benzylamine as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 230nMAssay Description:Inhibition of human VAP1 expressed in CHO cells using [14C]-benzylamine as substrate incubated for 30 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 230nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of rat liver DAO using putrescine as substrate after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MAOB expressed in CHO cells using benzylamine as substrate after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427008BDBM50427008(CHEMBL2326864)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DAO expressed in CHO cells using putrescine as substrate after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed