BDBM50427801 CHEMBL2325483

SMILES C[C@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(F)cc1

InChI Key InChIKey=ASDFSRNMHPUURW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427801   

TargetPhospholipase D1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427801(CHEMBL2325483)
Affinity DataIC50: 760nMAssay Description:Inhibition of PLD1 in human Calu-1 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427801(CHEMBL2325483)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of GFP-tagged PLD2 in human HEK293 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed