BDBM50427806 CHEMBL2325484

SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(Br)cc2)CC1

InChI Key InChIKey=PYFQAQXMZAWSDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427806   

TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427806(CHEMBL2325484)
Affinity DataIC50: 200nMAssay Description:Inhibition of GFP-tagged PLD2 in human HEK293 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427806(CHEMBL2325484)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of PLD1 in human Calu-1 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed