BDBM50428035 CHEMBL2324266
SMILES FC(F)(F)c1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccccc3)sc2c1
InChI Key InChIKey=KSTGTGUMVOFPSQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50428035
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
The University of Texas Southwestern Medical Center
Curated by ChEMBL
The University of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of rat recombinant CK1delta kinase domain using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of human recombinant CK1epsilon using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of rat GST-tagged CK1delta M82F mutant at 10 uM using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov ...More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of full-length rat GST-tagged CK1delta using alpha-casein as substrate after 30 mins in presence of [gamma-32P]-ATP by Cherenkov counting ...More data for this Ligand-Target Pair