BDBM50428121 CHEMBL2331674

SMILES NC(=O)CCNC(=O)C(CCCNC(=O)CN1C=C(CCC(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC2=CNC3=C2C=CC=C3)C(N)=O)N=N1)(CCCNC(=O)CN1C=C(CCC(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC2=CNC3=C2C=CC=C3)C(N)=O)N=N1)NC(=O)CNC(=O)CN1C=C(CCC(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC2=CNC3=C2C=CC=C3)C(N)=O)N=N1

InChI Key InChIKey=ZBGMRTGEBJPQMV-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50428121   

TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50428121(CHEMBL2331674)
Affinity DataKi:  4.30nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50428121(CHEMBL2331674)
Affinity DataKi:  11nMAssay Description:Displacement of Eu-DTPA-PEGO-NDP-alpha-MSH-NH2 from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50428121(CHEMBL2331674)
Affinity DataIC50: 14nMAssay Description:Displacement of Eu-NDP-alpha-MSH from human MC4R expressed in HEK293 cells by time resolved fluorescence binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed