BDBM50428603 CHEMBL2338405

SMILES CC(C)(C)NC(=O)NCCN1CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)CC1

InChI Key InChIKey=WEMURJPABSANLY-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50428603   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50428603(CHEMBL2338405)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:Inhibition of human T-type calcium channel Cav3.2 expressed in T-Rex293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50428603(CHEMBL2338405)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by IONWORKS assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50428603(CHEMBL2338405)Copy SMILESCopy InChI

Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6-mediated 7-methoxy-4(aminomethyl)-coumarine degradationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL