BDBM50428741 CHEMBL2333602

SMILES CCCCn1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1cc(ccc1C)-c1cccc2[nH]ncc12

InChI Key InChIKey=XZIADLYCTOCKRV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50428741   

TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 14nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 46nMAssay Description:Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 133nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 150nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 160nMAssay Description:Inhibition of Yes1 (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 203nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)
Affinity DataIC50: 264nMAssay Description:Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed