BDBM50429662 CHEMBL2335003

SMILES COc1ccc(cc1)-c1nc(CN2CCc3cc(OC)c(OC)cc3C2)cs1

InChI Key InChIKey=CILWRSDWEVZXPT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429662   

TargetATP-dependent translocase ABCB1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50429662(CHEMBL2335003)
Affinity DataEC50:  1.94E+3nMAssay Description:Activity at MDR1 (unknown origin) expressed in MDCK cells using calcein AM as substrate incubated for 30 mins prior to substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50429662(CHEMBL2335003)
Affinity DataEC50:  2.70E+3nMAssay Description:Activity at MRP1 (unknown origin) expressed in MDCK cells using calcein AM as substrate incubated for 30 mins prior to substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50429662(CHEMBL2335003)
Affinity DataEC50:  3.00E+4nMAssay Description:Activity at BCRP (unknown origin) expressed in MDCK cells using rhodamine 123 as substrate incubated for 30 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed