BDBM50429783 CHEMBL2337241

SMILES CCCC(C)Oc1ccc(cc1)C(=O)Nc1ccc2nc(SCC(=O)N[C@@H](C)c3ccccc3)sc2c1

InChI Key InChIKey=POIHUEXADQOJCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429783   

TargetSignal transducer and activator of transcription 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50429783(CHEMBL2337241)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HepG2 cells incubated for 1 hr followed by stimulation with IL-6 for 5.5 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50429783(CHEMBL2337241)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of STAT3 in IL-6-stimulated human HepG2 cells treated for 1 hr prior to IL-6 challenge measured after 5.5 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed