BDBM50429988 CHEMBL2334628

SMILES OC(c1ccc2nc([nH]c2c1)-c1ccc(OCc2ccccc2)cc1)c1ccccc1C(F)(F)F

InChI Key InChIKey=ZBFFRSOBUFXEKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50429988   

TargetAcyl-CoA desaturase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50429988(CHEMBL2334628)
Affinity DataIC50: 14nMAssay Description:Inhibition of SCD1 in rat H42E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50429988(CHEMBL2334628)
Affinity DataIC50: 82nMAssay Description:Inhibition of SCD1 in Wistar rat liver microsomes using [14C] stearic acid as substrate incubated for 10 mins prior to substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50429988(CHEMBL2334628)
Affinity DataIC50: 295nMAssay Description:Inhibition of SCD1 in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed