BDBM50431243 CHEMBL2333025

SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccncc1

InChI Key InChIKey=NFLFYUMFQNNIPE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50431243   

TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431243(CHEMBL2333025)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431243(CHEMBL2333025)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431243(CHEMBL2333025)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431243(CHEMBL2333025)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human DPP8 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431243(CHEMBL2333025)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed