BDBM50431392 CHEMBL2348851

SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(C(=O)NC(C)CO)c2n1

InChI Key InChIKey=IVTZBZBZVFLWIS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50431392   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431392(CHEMBL2348851)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431392(CHEMBL2348851)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431392(CHEMBL2348851)
Affinity DataIC50:  911nMAssay Description:Inhibition of SYK in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431392(CHEMBL2348851)
Affinity DataIC50:  256nMAssay Description:Inhibition of SYK in human Ramos cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed