BDBM50431521 CHEMBL2348864
SMILES O=C1CN(CCC2CCOCC2)c2nc(cnc2N1)-c1ccc(cc1)-c1nnc[nH]1
InChI Key InChIKey=MLNSAGOBCFMEKI-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50431521
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 526nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 526nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex subunit LST8(Homo sapiens)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mTORC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using GST-p70S6 as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair