BDBM50431715 CHEMBL2346728

SMILES COc1ccc(cc1)-n1c(C)nc(C(=O)Nc2cccc(C)n2)c1C

InChI Key InChIKey=UHSJOANGEBDQLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431715   

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431715(CHEMBL2346728)
Affinity DataIC50: 147nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed