BDBM50431942 CHEMBL2347847

SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1

InChI Key InChIKey=JFYUPKXGFNQNTK-UHFFFAOYSA-N

Data  7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50431942   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetA disintegrin and metalloproteinase with thrombospondin motifs 13(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ADAMTS-13 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetMatrix metalloproteinase-14(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP14 (unknown origin) by FRET methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

Target72 kDa type IV collagenase(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP2 (unknown origin) by FRET methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetStromelysin-1(Human)
Asahi Kasei Pharma

Curated by ChEMBL

LigandBDBM50431942(CHEMBL2347847)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin) by FRET methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL