BDBM50432648 CHEMBL2347386

SMILES CN1[C@@H]([C@@H](OCC1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1

InChI Key InChIKey=HLEJTSIQXVTYDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50432648   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432648BDBM50432648(CHEMBL2347386)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432648BDBM50432648(CHEMBL2347386)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant GST-thrombin-MDM2 (1 to 188) expressed in Escherichia coli assessed as reduction of MDM2-p53 interaction incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed