BDBM50433036 CHEMBL2375955

SMILES Cc1nc(N)nc2n([C@H]3CC[C@@H](CC3)OCC(N)=O)c(=O)c(cc12)-c1cn[nH]c1

InChI Key InChIKey=NNXNZTDFLLHLOS-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433036   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Mouse)
Pfizer

Curated by ChEMBL

LigandBDBM50433036(CHEMBL2375955)Copy SMILESCopy InChI

Affinity DataKi:  6.20nMAssay Description:Inhibition of mouse PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/12/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetRAC-alpha serine/threonine-protein kinase(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50433036(CHEMBL2375955)Copy SMILESCopy InChI

Affinity DataIC50: 256nMAssay Description:Inhibition of AKT phosphorylation at Ser 473 in human BT20 cellsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/12/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL