BDBM50433494 CHEMBL2381225

SMILES COc1ccc2CN(C(=O)c2c1)c1nc(cs1)C(=O)Nc1cncnc1N1CCNCC1

InChI Key InChIKey=ZLJKDNRLQXCYTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433494   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50433494(CHEMBL2381225)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant His-tagged CHK1 (unknown origin) expressed in baculovirus expression system using biotin-RSGLYRSPSMPENLNRPR as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed