BDBM50433602 CHEMBL2381980

SMILES C[C@H](Oc1nc(Nc2cc(C)n[nH]2)nc(N2CCOCC2)c1F)c1ncc(F)cn1

InChI Key InChIKey=NFYAORHLODKCQX-NSHDSACASA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433602   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433602(CHEMBL2381980)
Affinity DataKi:  0.720nMAssay Description:Competitive inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50433602(CHEMBL2381980)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed