BDBM50433847 CHEMBL2382398

SMILES COc1ccc(NC(=O)CSc2nc(-c3ccc(Cl)cc3)c(C#N)c(=O)[nH]2)cc1Cl

InChI Key InChIKey=GRVUDEJFCXAUOB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433847   

TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50433847(CHEMBL2382398)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate after 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50433847(CHEMBL2382398)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50433847(CHEMBL2382398)
Affinity DataKd:  6.40E+5nMAssay Description:Binding affinity to human recombinant carboxy-terminal avi-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed