BDBM50434355 CHEMBL2386745

SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(F)cc4OC)c3c2s1

InChI Key InChIKey=ZPXSIWLYMMFFCE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434355   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50434355(CHEMBL2386745)Copy SMILESCopy InChI

Affinity DataIC50: 0.360nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy BDB DOIPubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Dart Neuroscience

Curated by ChEMBL

LigandBDBM50434355(CHEMBL2386745)Copy SMILESCopy InChI

Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL