BDBM50434410 CHEMBL2387450

SMILES CC(C)CNC(=O)C(C)(C)C[C@H](O)[C@@H](N)CN1CC(=O)N(CC1(C)C)c1cc(F)ccc1Cl

InChI Key InChIKey=MNPZPSAKVWLMFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434410   

TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434410BDBM50434410(CHEMBL2387450)
Affinity DataIC50: 97nMAssay Description:Inhibition of human recombinant renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (DABCYL)-Arg as substrate incubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434410BDBM50434410(CHEMBL2387450)
Affinity DataIC50: 738nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 1 hr by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed