BDBM50434420 CHEMBL2387572

SMILES CC(C)[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(CC1(C)C)c1cc(F)ccc1Cl)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key InChIKey=YLBAJFNJBXXSBQ-UZSLBGTOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434420   

TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434420(CHEMBL2387572)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 1 hr by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50434420(CHEMBL2387572)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (DABCYL)-Arg as substrate incubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed