BDBM50434654 CHEMBL2387465

SMILES O=C(Nc1c[nH]c2ncc(-c3c(F)cccc3F)cc12)c1cnn2ccc(NC[C@H]3CCNC[C@@H]3F)nc12

InChI Key InChIKey=TWIFKBILIHXMMI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434654   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434654BDBM50434654(CHEMBL2387465)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of PIM1 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434654BDBM50434654(CHEMBL2387465)
Affinity DataKi:  0.0190nMAssay Description:Inhibition of PIM3 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434654BDBM50434654(CHEMBL2387465)
Affinity DataKi:  0.0370nMAssay Description:Inhibition of PIM2 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed